Acute Fatty Liver of PregnancyCreated by:
Acute fatty liver of pregnancy is a rare disorder in pregnancy, occur in 1 in 13000 to 16000 pregnancies. It can occur in second, or third trimester, occassionally postpartum. Patient will presented with jaundice, lethargy, nausea, vomitin, and altered mental status. Blood tests may show moderate ALT/AST elevations, conjugated hyperbilirubinemia, high PT, fibrin splits products, D-dimer, low platelet, high amonia level, serum uric acid and leukocytosis. In the severe situation, a rapid progress to hypoglcemia, disseminated intravascular coagulation, renal impairment, coma or death can occur. Anyone has any experience in this rare disorder in pregnancy ?? What are the management strategy ?