Issue on TamifluCreated by:
Since the outbreak of swine flu (H1N1 virus) in April 2009, the prescription of oseltamivir for flu-like symptoms have increased. This was based on research studies that neuraminidase inhibitors will reduce the length of the disease course, decrease hospital admissions and the incidence of associated influenza complications. However, there are researchers that criticize the original studies on the efficacy of neuraminidase inhibitors. In fact, in 2006, a team of Cochrane researchers performed a systematic analysis on available data and concluded that neuraminidase inhibitors should not be prescribed for seasonal flu, but it can be used as a public health precautionary measure in cases of flu pandemics. Another published Cochrane review last 2014 confirms that there are small benefits on symptom relief, shortened duration of symptoms by 0.5 days (average). However there is little evidence that it prevents development of complications such as pneumonia. This review also suggests that neuraminidase inhibitors prevent disease person-person transmission. Do you think its worth it to prescribe Oseltamivir? Have you seen any significant benefit from it?