Paracetamol poisoning: 3 things that a pharmacist should know

Paracetamol poisoning: 3 things that a pharmacist should know

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Paracetamol poisoning is a severe and potentially life-threatening medical emergency. The medicine is widely available as a popular over-the-counter remedy, therefore it is not surprising that incidences of Paracetamol poisoning is commonplace in many countries. It is also indicated as the most prevalent drug misused in either accidental overdose or intentional suicidal attempts (1).
9 Aug 2016 - General
Paracetamol toxicity is becoming more of an issue due to the number of paracetamol-containing products on available on the market. cold and flu medications contain paracetamol. My pet hate is when they market different cold and flu medications. One will be targeted to sinus and allergies, another will be for colds, or another may be for sinus pain. All of which will contain paracetamol. Patients may be unaware and could take cold and flu medication as well as paracetamol alone, unknowingly doubl...
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Intentional overdose of Paracetamol is very common in Sri Lanka. That is partly due to the fact that paracetamol is cheap and widely available as an over the counter analgesic/antipyretic. Secondly people are quite aware about the toxicity of paracetamol and they think ingesting 30 tablets is going to kill them when what really happens is that they are going to suffer a lot due to acute liver injury. The antidote for paracetamol poisoning is N-acetylcysteine which is a very expensive drug, but ...
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Paracetamol is a very popular drug for fever and pain in the Philippines. It is relatively safe and can be taken with an empty stomach. Unlike NSAIDs, it is not notorious for causing possible cardiac arrest and gastrointestinal bleeding. However, one major drawback with its use is hepatotoxicity. Hepatocellular necrosis will occur upon ingestion of 4 grams of paracetamol in a day; hence, clinicians more often set a limit of Paracetamol intake at 2-2.4 grams per day. Extra caution must be exercis...
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