Ulcerative Colitis - Managment Plan

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3 Sep 2016 - General

There are a few medications that are available to treat ulcerative colitis, like steroid (intravenous hydrocortisone or oral prednisiolone), 5-aminosalicylic acid (5-ASA)/mesalazine, azathioprinne, biologic agent (Infliximab, adalimumab, golimumab), and bio-simillar product. In an acute flare of colitis or 1st presentation of acute colitis, intravenous steroid is required to induce remission of the disease activity, and patient can be started with mesalazine to maintain the remission of disease activity. Azathioprine is the next step if patient has reccurrent flare with mesalazine or no effect from mesalazine. The next step will be biologic agent. Rescue therapy with Infliximab can be used as well for patient with acute flare of colitis that was not responed to intravenous steroid. Some specialist do use cyclosporin as well.

Yes, Rajinda Asalage 5-ASA / Mesalazine is very useful in maintaining patient with ulcerative colitis in clinical remission. But, it is not as useful in the case of acute flare of colitis. ...
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A patient with mild symptoms can be manage symptomatically. For loose stools, anti-diarrheals. Dietary habits can be modified to reduce loose stools. Aminosalicylates can be used to relieve the inflammation inside the intestine and steroid drugs also...
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