Maturity Onset Diabetes of The Young (MODY)

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4 Sep 2016 - General

Type 1 Diabetes and Type 2 Diabetes are not the only sub-type of Diabetes, there are a lot of other different form of diabetes like Maturity Onset Diabetes of The Young (MODY). MODY is a rare form of diabetes, caused by a mutation of a single gene. It is different from Type 1 or 2 Diabetes. The genetic mutation can be passed on to the children. There are 50% of the child to inherited MODY if the parent has this gene mutation.There are a few different sub-types of MODY like HNF1-alpha, HNF4-alpha, HNF1-beta, and glucokinase. The characteristic features of MODY are being diagnosed with diabetes before the age of 25, having a parent with diabetes, with diabetes in two or more generation, and not necessarily reqired insulin.

Most of the doctors misdiagnose maturity onset diabetes of the young (MODY) as type 1 diabetes mellitus or type 2 diabetes mellitus. For the diagnose purposes three key features have been described. The person should be diagnosed to have diabetes before 2 years of age. And one of the parents should have had diabetes in two or more generations. The other key feature is the particular person should have the need of insulin. MODY appears not because of a result of a metabolic process but can lead i...
 (Total 135 words)
Maturity onset diabetes, or MODY is not a single disease entity. MODY is considered as a diagnosis in many types of diabetes that is caused by a mutation in an autosomal dominant gene. It is the final diagnosis in about 1%–2% of patients who are initially diagnosed with diabetes from blood testing and then genetic testing done later to identify the type of diabetes. The prevalence of MODY is said to be about 70–110 per million population. That is not a rare occurrence. The problem with MODY is t...
 (Total 113 words)