General

Crohns Disease : Researchers may have found the cause?

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29 Sep 2016 - General
 

Bacteria and fungal species are identified in crohns disease patients.

The results showed strong fungal-bacterial interactions in those with Crohn’s disease: two bacteria – E.coli and Serratia marcescens – and one fungus called Candida tropicalis. The presence of all three in those with Crohn’s disease was significantly higher compared to their healthy relatives, suggesting that the bacteria and fungus interact in the intestines.

So new additive treatment with antibiotics needed?

Please comment!

That sounds good because we should know the cause to treat a disease. Crohns disease is one of the two types of the inflammatory bowel diseases and usually affects the last part of the small intestine and the initial part of the large intestine. It may cause ulcers in the intestinal wall, obstruction to the lumen of the digestive pathway and the serious and life threatening complications like perforation of the bowels. There is a known risk of developing colonic cancers following crohns disease....
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Finding a direct causative factor for crohn's disease has been a challenge to gastroenterologists. The disease is believed to be the reaction of the host immune system to a variety of environmental factors and genetics also seem to play a role in its pathogenesis. It can be completely due to a genetic mutation, but sometimes the pattern of inheritance that we would expect to see is not there to completely accept that theory. The discovery of strong fungal-bacterial interactions in people wit...
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I feel these finding will make scientists to look again on the pathogenesis of crohn's disease. Currently we don't use antibiotics or antifungals to treat Crohn's disease unless there are complications. But these findings will definitely open a discussion to change or modify the regime of treating the diaease. But here I have one question for you @Madhubabu kaaja. Are they saying that bacterial and fungal growths are as a cause of the disease or are these growths common among patient...
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