General

Anaemia in Patient with Chronic Kidney Disease

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5 Nov 2016 - General
 

There are a lot of different causes for chronic renal impairment, like diabetes mellitus, hypertension, polycystic kidnes disease, glomerulonephritis,and  obstructive uropathy. The reduction of renal function can be progressive, with stage I to V Chronic Kidney Disease. In patient with chronic kidney disease, the prodcution of erythropoietin can be reduced. As GFR falls, the prodcution of erythropoietin can be falling as well, leading to lower haemoglobin level. The pattern of anaemia in this case will be usually normochromic normocytic anaemia. Patient will let more lethargy, fatigue when the haemoglobullin is dropping. The treatment option for anaemia secondary to chronic kidney disease will be the recombinant erythropoietin, aim to maintain the haemoglobin above 10.5 g/DL. Close monitoring of haemoglobin is required in patient with chronic kidney impairment.

Out of hundred and one problems chronic kidney disease can give rise to, anemia is one of the most important challenges physicians have to face when managing a patient with chronic kidney disease. Fluid retention due to impaired renal function increases the workload on the heart and this stress can lead to heart failure. In the presence of anemia this the risk of developing heart failure is higher because the heart has to do an additional work to maintain tissue oxygenation when there is low hem...
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Yes Marinelle Castro , would totally agree that treatment with recombinant erythropoietin is very costly. The affordability can be varied depend on different healthcare system and patient cohort. It will be a great burden for the patient or the family, if they need to pay for it themselves!! Another point to add, we should always check for potential iron deficiency as well, and we can always replace the iron stor...
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Malaise, palpitations and shortness of breath are the usual symptoms of anemia and those are often experienced by the people who are having chronic kidney injury. Chronic kidney injury may be precipitated by poly cystic kidney disease, an obstructive uropathy, as a complication of diabetes mellitus which is diabetic nephropathy, chronic hypertension or the changes of the constitution of the drinking water. Anyhow when the kidneys are damaged due to these conditions, they fail to produce erythrop...
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You Yi Hong Chronic Kidney disease is a silent illness. I have encountered a lot of patients who were diagnosed because of severe anemia. They usually present with pallor, dizziness or easily fatigability. This gets complicated when they have to go through renal replacement therapy because as you said, hemoglobin has to be maintained at least at 10g/dl. Most patients require at least once per weekly injection, a...
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