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20 Nov 2016 - General

An elderly gentleman, with background of stroke, hypertension, ischaemic heart disease, peripheral vascular disease, mild cognitive impairment and chronic obstructive lung disease, was admitted to hospital due to 3 days history of bloody diarrhoea. He was recently discharged from hospital around 5 days ago, after being treated with a course of antibiotic for his infective exacerbation of chronic obstructive lung disease, with 1 week of hospital stay. He was well after discharged, but started to develop bloody diarrhoea up to 5-6 times a day since 3 days ago, accompany with slight minimal general abdominal discomfort. On examination, there was minimal tenderness around abdomen. Blood tests showed normal full blood count, with slight elevated inflammatory marker (CRP). X-ray of abdomen and chest were normal. What is your working diagnosis ? What are the investigation and treatment for this patient ?

The clinical practice guidelines for Clostridium difficile infection in adults states that the diagnosis of CDI should be based on a combination of clinical and laboratory findings. A case definition for the usual
presentation of CDI includes the...
 (Total 84 words)
Yes, the likely working diagnosis will be Clostridium difficile infective diarrhoea. Patient is having a very high risk of getting this infection due to recent hospitalisation and antibiotic usage. Stool sample can be sent to detect clostridium diffi...
 (Total 106 words)
It is a probable case of antibiotic-associated diarrhoea caused by Clostridium difficile. It is also termed as pseudomembranous colitis.
C. difficile is an opportunistic pathogen which lives in the intestine and usually does not produce a proble...
 (Total 126 words)