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Is medical research chasing its tail by relying too much on mouse models?
 

Is medical research chasing its tail by relying too much on mouse models?

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Do mouse models, the backbone of medical research, properly predict human diseases? The evidence suggests this is less true than previously thought.
 
today.mims.com
 
8 Dec 2016 - General
 
Marinelle Castro some animals are more similar to humans on which we are studies safety and toxicology studies. It is a preliminary screening of a new drug before testing on a human beings ...
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Marinelle Castro During preclinical experiments animals may suffer and appropriate justification required to provide appropriate justification for outcome of experimental result. The rise in animal model utilization is due to a raised diseases and th...
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Jennifer Winter It is good to use mice in preclinical studies and drug development process as well. Moreover pharmacological and toxicological data is based on studies in mice only. Mice is...
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Mice have a high homology with humans which is why they are used as test subjects. It is difficult to use humans as tests subjects as there is a lot of ethical and moral implications in doing so (as ...
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Of course drug research on neurological diseases mostly rely on animals because outright drug testing on humans brings about ethical issues. I understand that this issue is significant because of the problems in translational research. However, it is...
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Scientists have long relied on mouse models for human disease exploration and drug candidate evaluation. The benefits to humans, in certain diseases and mouse models, have shrunk to such low levels that it’s time we found better ways to work with ani...
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Mice fill a special and important role in medical research. Like humans, mice are mammals, and their bodies undergo many similar processes, such as ageing, and have similar immune responses to infection and disease.

What we can use an alter...
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