General
Glimepiride carries added hypoglycaemia risk in certain elderly patients with T2D
 

Glimepiride carries added hypoglycaemia risk in certain elderly patients with T2D

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The sulfonylurea glimepiride may pose an increased risk of hypoglycaemia in a subgroup of elderly type 2 diabetes (T2D) patients with lower β-cell function when added to a metformin regimen, according to a post-hoc analysis of data from the GENERATION* trial.
 
specialty.mims.com
 
9 Jan 2017 - General
 
Glimepiride and metformin combination therapy is widely used in India for management of type 2 diabetes. The study showing that hypoglycemia is more seen in old age patients with age more than 75 years and also significant between ages of 65-75 years.Cause for raise in blood glucose is due to a raise in insulin levels independently with blood glucose level, so there is an availability of insulin to reduce further in glucose levels which in terms said as hypoglycemia. So, it is better to switc...
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In my practice everyday in the wards, we will never miss patients who are diabetic. May it be juvenile diabetes mellitus, type 1 or 2 diabetes mellitus and gestational diabetes mellitus. This has been a very sensational condition accross all groups around the world. And what I've noticed, patients are taking mostly either gliclazide and metformin. Good to know that this controlled study is showing lower risk of having hypoglycemia for those who were taking metformin and saxagliptin compared ...
 (Total 91 words)