Wound Healing Effects of Tinospora cripa Identified

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28 Jun 2016 - General

Through the years, Tinospora crispa has been studied for its hypoglycemic and insulinotrophic properties but in a recent study by Arcueno, R., Retumban, J. et al., of Bicol University College Nursing from the Philippines also suggests its potential wound healing effects from the plant extract. Ethanolic extraction of Tinospora crispa stem was used to treat incised wounds from diabetes induced male albino mice. Experimental groups where divided as follows: Group A with no treatment observed (negative control); Group B treated with the plant extract once a day and commercial antibiotic; Group C treated with the plant extract only; and Group D with commercial antibiotic (positive control). After 14 days of treatment, upon gross examination, Groups B and C suggests that the commercial antibiotic seems not to hasten the wound healing effect and  suggestive that it might be brought the hypoglycemic property of the plant extract thereby increasing blood circulation in the affected area, and maybe secondary from the action of the antibiotic. Average epithelialization from the groups was faster in average of 12 days compared to Group A with 18 days and Group D with 15 days. Histologic evidence showed that from Group A and Group B showed mild chronic inflammation in the dermis, moderate epidermal necrosis but with negative ulceration and granulation tissue; while Group C showed no chronic inflammation in the dermis, with moderate epidermal necrosis and has no negative ulceration and granulation tissue. Based from the study, it proves that Tinospora crispa has biochemical compounds that can be used in improving the treatment, care and management of Diabetic clients.