BMI as one of the predisposing factors in breast cancer

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17 Jul 2016 - General

Body mass index (BMI) is a measure used to define body weight status (normal, overweight and obese).  It includes a measure of height and weight, so it is a better comparison of body weight status than weight alone.

Breast cancer is cancer that develops from breast tissue. Risk factors for developing breast cancer include: female sex, obesity, lack of physical exercise, drinking alcohol, hormone replacement therapy during menopause, ionizing radiation, early age at first menstruation, having children late or not at all, older age, and family history.

There are many studies conducted linking BMI to breast cancer risk.  Gaining weight in adulthood appears to increase the risk of breast cancer before and after menopause. One large study found that women who gained about 20 pounds after age 18 had a 15 percent higher risk of breast cancer compared to women who gained little or no weight. Women who gained 55 pounds or more had a 45 percent higher risk.

What are your thoughts on this?

Many studies have shown that overweight and obesity are associated with a modest increase in risk of postmenopausal breast cancer. The relationship between obesity and breast cancer may be affected by the stage of life in which a woman gains weight and becomes obese. The increased risk of postmenopausal breast cancer is thought to be due to increased levels of estrogen in obese women. After menopause, when the ovaries stop producing hormones, fat tissue becomes the most important source of estro...
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Hi Hannah, although BMI is easier to measure, it does not distinguish between excess muscle, fat, or bone mass. I think what this research is trying to do is to look for an clinically useful objective marker that will indicate excess fat stores. In my opinion, waist circumference and waist-hip ratio are more predictive of excess body fat. Hence, these will be more objective markers of excess body fat. Since adipose tissue is now already considered an endocrinologic organ because it is hormone-se...
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Yes, would agree that increased in body mass index will be a risk factor of breast cancer. Increasing in weight (BMI of either overweight or obese) will be risk factor for a significant amount of a variety of medical conditions, including breast cancer. Nowadays, with the increasing widely availability of fast food and processed food, the prevalence of obesity around the world is increasing. And this is associated with negative health impact for the population. There will be a lot more of healt...
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