Decision for treatment for chronic hepatitis B, when should we treat ???Created by:
When should we treat patient with chronic hepatitis B ?? Not all the patients with chronic hepatitis B will be benifit from the treatment. The cohort of patients with chronic hepatitis B that will benefit from treatment are patients with detectable viremia and evidence of ongoing liver necrosis (like increasing liver enzyme, liver biopsy showed active inflammation or fibrosis). Patients will usually test positive for hepatitis B e antigen (HBeAg), and negtive for HBe antibodies (HBeAb), with high level of hepatitis B virus DNA. Patients that are chronic hepatitis B carriers, with HBsAg positive, HBeAg negative, HBeAb positive, non-detectable or low HBV DNA viral load, do not require active antiviral treatment, will only require monitoring.